Volume 8, Issue 3, September 2020, Page: 54-64
Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma
Heba Samier, Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Hazem Omar, National Liver Institute, Menoufia University, Menoufia, Egypt
Rasha Dawoud, Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Alsiagy Ali Salama, Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Abd-Elmonem Nooman, Department of Radiology, Faculty of Medicine, Tanta University, Tanta, Egypt
Received: Sep. 19, 2020;       Accepted: Oct. 5, 2020;       Published: Oct. 12, 2020
DOI: 10.11648/j.ijmi.20200803.14      View  71      Downloads  18
There are many treatment options available for hepatocellular carcinoma (HCC) but the best choices for intermediate and advanced tumors are sometimes a matter of controversies. The aim of the work was to compare the combined Trans-catheter arterial chemoembolization (TACE) with percutaneous ethanol injection (PEI) against the technique of TACE alone in patients with unresectable HCC. The study included fifty patients proved radiologically to have hepatocellular carcinoma (HCC) >5 cm in diameter and were not candidate for surgical resection. The patients were divided into two groups Group 1: Patients underwent single Trans-catheter arterial chemoembolization (TACE) followed by four times of Percutaneous ethanol injection (PEI) every other day. Group 2: Patients underwent repeated Trans-catheter arterial chemoembolization (the frequency of sessions was according to response of the patients). Complete resolution of HCC masses achieved in 60% in group 1 versus 52% in group 2. This complete resolution occurred earlier in group 1 than group 2. Group 1 had lower local recurrence rate than group 2. There was a statistically significant reduction in alpha-feto protein level at 3 months post interventional in group 1 and in both groups at 6 months. There was no significant difference between both groups in overall survival, So combined treatment could help in saving time and resources.
Trans-catheter Arterial Chemoembolization, Percutaneous Ethanol, HCC
To cite this article
Heba Samier, Hazem Omar, Rasha Dawoud, Alsiagy Ali Salama, Abd-Elmonem Nooman, Evaluation of Combined Transcathter Arterial Chemo Embolization (TACE) with Percutaneous Ethanol Injection (PEI) Vs. (TACE) for Unresectable Hepatocellular Carcinoma, International Journal of Medical Imaging. Vol. 8, No. 3, 2020, pp. 54-64. doi: 10.11648/j.ijmi.20200803.14
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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