An Assessment of the Size of Sella Turcica Among Adult Nigerians Resident in Lagos
Ogunnaike Philip Olubunmi,
Olatunji Sunday Yinka,
Owolabi Joshua Oladele,
Ginigeme Anita Adimchukwunaka,
Olanrewaju John Afees
Issue:
Volume 4, Issue 3, May 2016
Pages:
12-16
Received:
19 May 2016
Accepted:
2 June 2016
Published:
20 June 2016
Abstract: One of the clinical significance of the sella turcica is the empty sella syndrome which is the condition of a shrunken or flattened pituitary gland; hence a familiarity with the sella turcica anatomy and radiological appearance is of great importance. The present study investigated the normal dimensions of the sella turcica and the relationship with gender and age in adult Nigerians resident in Lagos, using computed tomographs of patients who underwent CT head examination. This was carried out to determine if the dimensions of sella turcica vary with age, gender and race; this is with a view to providing normal, standard reference for the indigenous population in Nigeria. This study assessed: the length, the depth and the antero-posterior diameter of the sella turcica; 297 samples were obtained and analyzed using SPSS Windows Version 14.0. T- test was used for the statistical analysis and values obtained were expressed as mean±S.E.M. and P value ˂ 0.05 was considered statistically significant. The results showed the mean length of 9.81±0.094mm; the mean antero-posterior diameter of 11.37±0.090mm and the mean depth of 8.49±0.08mm. It was also observed that neither the age group nor the gender of the patients is a determinant of the sella turcica dimensions. Furthermore, the males tend to have slightly larger sella turcica dimensions than the females and the values from the present study are lower than those reported in Caucasian studies. The size of pituitary gland can be roughly estimated from the dimensions of sella turcica obtained from radiological methods in pathological conditions since disease conditions of the “master gland” ultimately affect the size of the sella turcica.
Abstract: One of the clinical significance of the sella turcica is the empty sella syndrome which is the condition of a shrunken or flattened pituitary gland; hence a familiarity with the sella turcica anatomy and radiological appearance is of great importance. The present study investigated the normal dimensions of the sella turcica and the relationship wit...
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The Problem of Nephropathy Induced by Endocavitary Administration of Iodine-Containing X-ray Contrast Agents
Iliya Mikhailovich Strekalov,
Leonid Petrovich Larionov,
Мikhail Georgievich Zuev,
Elena Yuryevna Zhuravleva
Issue:
Volume 4, Issue 3, May 2016
Pages:
17-22
Received:
16 June 2016
Accepted:
5 July 2016
Published:
18 July 2016
Abstract: It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administration. The achieved results have shown the absence of general toxic effect on bodies of animals, high X-ray contrast properties in vitro and in vivo experiments. The investigations were performed on white nondescript mice, rats Wistar subtype and Chinchilla rabbits.
Abstract: It is known that there is a high risk of progression of side effects in kidneys, so-called nephropathy induced with X-ray contrast agents, at applying of water-soluble X-ray contrast agents in medical practice. New water-insoluble compounds of orthotantalates of rare-earth elements are offered as new X-ray contrast agents for endocavitary administr...
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